γδ T cells are not alone

Th17 cells are not required for maintenance of IL-17A producing γδ T cells in vivo

γδ T cells producing interleukin-17A (γδT17) are thought to develop spontaneously in the thymus and to be maintained in the periphery. Previous studies suggested a role for T-helper 17 (Th17) cells in the maintenance of γδT17 via the expression of transforming growth factor-β1 (TGFβ1). However, we have previously found that Th17 cells were not required for expansion of γδT17 cells after lung tr...

You are not alone.

A DBT Support Group may be able to benefit you. DBT (Dialectical Behavior Therapy) is a proven approach to therapy used to help persons who have difficulty managing emotions. • Like you keep "losing it?" • Like you have problems with anger and/or high levels of anxiety? • Drastic mood swings/ quickly shifting from one emotion to another? • Like harming yourself in any way? • Like relationships ...

You are not alone!

Cardiac Stem Cells for Myocardial Regeneration: They Are Not Alone

Heart failure is the number one killer worldwide with ~50% of patients dying within 5 years of prognosis. The discovery of stem cells, which are capable of repairing the damaged portion of the heart, has created a field of cardiac regenerative medicine, which explores various types of stem cells, either autologous or endogenous, in the hope of finding the "holy grail" stem cell candidate to slo...

Bovine γδ T Cells Are a Major Regulatory T Cell Subset

In humans and mice, γδ T cells represent <5% of the total circulating lymphocytes. In contrast, the γδ T cell compartment in ruminants accounts for 15-60% of the total circulating mononuclear lymphocytes. Despite the existence of CD4(+)CD25(high) Foxp3(+) T cells in the bovine system, these are neither anergic nor suppressive. We present evidence showing that bovine γδ T cells are the major reg...